Panama and Brazil are partners in many efforts involved in limiting the spread of the zika virus through programs such as nuclear sterilization of mosquito transmitters and vaccines - The two countries are also signatories of a treaty of scientific, artistic and literary exchange since as early as 1944.

Brazil has traditionally been very active in communication with all Latin American countries, including Panama - in December 2008 brazil initiated the first summit of the Community of Latin America and Caribbean States, calc, which was held in bahia and in which the goal was to launch cooperative projects in the areas of education, culture, transport, energy and infrastructure.